| Bioactivity | Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC50s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2)[1]. |
| Name | Cochliodone A |
| CAS | 1072931-48-6 |
| Formula | C34H38O12 |
| Molar Mass | 638.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang W, et al. Chlorinated Azaphilone Pigments with Antimicrobial and Cytotoxic Activities Isolated from the Deep Sea Derived Fungus Chaetomium sp. NA-S01-R1. Mar Drugs. 2018 Feb 13;16(2):61.. |
Cochliodone A
CAS: 1072931-48-6 F: C34H38O12 W: 638.66
Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antiba
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