Bioactivity | Closantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing. |
CAS | 57808-65-8 |
Formula | C₂₂H₁₄Cl₂I₂N₂O₂ |
Molar Mass | 663.07 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |