Clofibride

CAS: 26717-47-5 F: C16H22ClNO4 W: 327.80

Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and mar

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Bioactivity	Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo[1].
In Vivo	Clofibride (oral, 400; 500 and 1000 mg/kg; single) can rapidly and massively resorb and hydrolys into 4chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) [1]. Animal Model:
Name	Clofibride
CAS	26717-47-5
Formula	C16H22ClNO4
Molar Mass	327.80
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. G P Loiseau, et al. On the metabolism of clofibride, a hypolipaemic drug. J Pharm Pharmacol. 1980 Jul;32(7):483-8.