PeptideDB

Clivatuzumab

CAS: 1622075-09-5 F: W:

Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pa
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Bioactivity Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers[1].
Invitro Clivatuzumab 对胰腺导管腺癌 (PDAC) 表现出高特异性,对正常和良性非肿瘤性胰腺组织几乎没有反应性,尽管它对某些其他器官(如胃、结肠、肺)的腺癌表现出有限的反应性(约占所有样本的 10%)[1]。
Name Clivatuzumab
CAS 1622075-09-5
Appearance Liquid
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Gold DV, et al. Mapping PAM4 (clivatuzumab), a monoclonal antibody in clinical trials for early detection and therapy of pancreatic ductal adenocarcinoma, to MUC5AC mucin. Mol Cancer. 2013 Nov 20;12(1):143.