| Bioactivity | Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively. |
| CAS | 22431-46-5 |
| Formula | C18H33ClN2O6S |
| Molar Mass | 440.98 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wynalda, et al. In vitro metabolism of clindamycin in human liver and intestinal microsomes. Drug Metab. Dispos. 31(7), 878-887 (2003). |
Clindamycin Sulfoxide
CAS: 22431-46-5 F: C18H33ClN2O6S W: 440.98
Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of
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