Bioactivity | Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis[1]. |
CAS | 2309313-01-5 |
Formula | C39H37N7O8 |
Molar Mass | 731.75 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bicker K L, Subramanian V, Chumanevich A A, et al. Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination[J]. Journal of the American Chemical Society, 2012, 134(41): 17015-17018. |