Bioactivity | Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV)[1]. |
Target | HRV, Bacterial. |
Name | Citrullinated LL-37 3cit |
Sequence | Leu-Leu-Gly-Asp-Phe-Phe-{Cit}-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-{Cit}-Ile-Val-Gln-{Cit}-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
Shortening | LLGDFF-{Cit}-KSKEKIGKEFK-{Cit}-IVQ-{Cit}-IKDFLRNLVPRTES |
Formula | C205H337N57O56 |
Molar Mass | 4496.22 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Casanova V, et al. Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection. Front Immunol. 2020 Feb 4;11:85. |