| Bioactivity | Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities. | ||||||||||||
| In Vivo | Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds[1]. | ||||||||||||
| Name | Cirsimaritin | ||||||||||||
| CAS | 6601-62-3 | ||||||||||||
| Formula | C17H14O6 | ||||||||||||
| Molar Mass | 314.29 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Abdelhalim A, et al. Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis. J Pharm Pharm Sci. 2015;18(4):448-59. |
Cirsimaritin
CAS: 6601-62-3 F: C17H14O6 W: 314.29
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinocicep
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.