| Bioactivity | Cinoxacin-d5 is the deuterium-labeled Cinoxacin (HY-B1085)[1]. Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis[2][3]. |
| Target | MIC: 4-64 μg/mL (Gram-negative aerobic bacteria) |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 |
| Name | Cinoxacin-d5 |
| CAS | 2732985-25-8 |
| Formula | C12H5D5N2O5 |
| Molar Mass | 267.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |
Cinoxacin-d5
CAS: 2732985-25-8 F: C12H5D5N2O5 W: 267.25
Cinoxacin-d5 is the deuterium-labeled Cinoxacin (HY-B1085). Cinoxacin (Compound 64716), a synthetic antimicrobial relate
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This product is for research use only, not for human use. We do not sell to patients.