| Bioactivity | Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions[1]. Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS[2]. | ||||||||||||
| Invitro | The effect of Cimifugin (Cimitin) on TSLP decreases significantly when expression of CLDN1 is interfered with siRNA and this implied Cimifugin inhibits initiative cytokines through restoring TJs[1]. | ||||||||||||
| Name | Cimifugin | ||||||||||||
| CAS | 37921-38-3 | ||||||||||||
| Formula | C16H18O6 | ||||||||||||
| Molar Mass | 306.31 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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