Bioactivity | Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway[1]. |
Invitro | Chrysomycin A (0.2-1.8 μM; 48 h) 具有抗胶质母细胞瘤作用,抑制 U251 和 U87-MG 人胶质母细胞瘤的细胞活力,以及迁移和侵袭[1]。Chrysomycin A (0.2-1.8 μM; 48 h) 抑制 U251 和 U87-MG 细胞中 Akt/GSK-3β/β-Catenin 信号通路[1]。 Cell Viability Assay[1] Cell Line: |
Name | Chrysomycin A |
CAS | 82196-88-1 |
Formula | C28H28O9 |
Molar Mass | 508.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |