| Bioactivity | Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID50 of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine[1]. |
| CAS | 133633-11-1 |
| Sequence | Ser-Asp-Glu-Asp-Ser-Asp-Gly-Asp-Arg-Pro-Gln-Ala-Ser-Pro-Gly-Leu-Gly-Pro-Gly-Pro |
| Shortening | SDEDSDGDRPQASPGLGPGP |
| Formula | C78H120N24O35 |
| Molar Mass | 1953.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Galindo E, et al., Chromostatin, a 20-amino acid peptide derived from chromogranin A, inhibits chromaffin cell secretion. Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1426-30. |
Chromostatin (bovine)
CAS: 133633-11-1 F: C78H120N24O35 W: 1953.93
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced
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