Bioactivity | Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2]. |
CAS | 55357-38-5 |
Formula | C12H21NO4S |
Molar Mass | 275.36 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265(5):2657-64. [2]. Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014. |