| Bioactivity | Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect[1]. |
| Target | PPAR |
| In Vivo | Choline Fenofibrate exhibits excellent absolute oral bioavailability (rat 93.4%) and Cmax (rat 7944.2 ng/mL) following oral administration (rat 4mg/kg)[1].Choline Fenofibrate exhibits terminal elimination half-life (rat 5.4 h) following intravenous injection (rat 4mg/kg)[1]. Animal Model: |
| Name | Choline Fenofibrate |
| CAS | 856676-23-8 |
| Formula | C22H28ClNO5 |
| Molar Mass | 421.91 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Xudan Wei, et al. Absolute oral bioavailability of fenofibric acid and choline fenofibrate in rats determined by ultra-performance liquid chromatography tandem mass spectrometry. Biomed Chromatogr. 2017 Apr;31(4). |
Choline Fenofibrate
CAS: 856676-23-8 F: C22H28ClNO5 W: 421.91
Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastro
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