PeptideDB

Cholic acid 7-sulfate

CAS: 60320-05-0 F: C24H40O8S W: 488.63

Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist
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Bioactivity Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholic acid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion[1].
Target TGR
Name Cholic acid 7-sulfate
CAS 60320-05-0
Formula C24H40O8S
Molar Mass 488.63
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Chaudhari SN, et, al. Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects. Nat Chem Biol. 2021 Jan;17(1):20-29.