| Bioactivity | Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel. | ||||||||||||
| Invitro | Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate[1]. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition[1]. | ||||||||||||
| Name | Cholesterol myristate | ||||||||||||
| CAS | 1989-52-2 | ||||||||||||
| Formula | C41H72O2 | ||||||||||||
| Molar Mass | 597.01 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Cholesterol myristate
CAS: 1989-52-2 F: C41H72O2 W: 597.01
Cholesterol myristate is a natural steroid present in traditional Chinese medicine.Cholesterol myristate binds to severa
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