| Bioactivity | Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells[1]. |
| Invitro | Chol-N3 (25 μM; 16 小时; 活的 SH-SY5Y 细胞) 在活细胞中的分布清楚地表明了质膜 (PM) 中纳米级结构域的存在[1]。Chol-N3 (15 μM; 16 小时) 在 SH-SY5Y 细胞中具有纳米级时空扩散动力学[1]。 |
| Name | Chol-N3 |
| CAS | 2106868-12-4 |
| Formula | C24H39N3O |
| Molar Mass | 385.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lorizate M, et, al. Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells. Small Methods. 2021 Sep;5(9):e2100430. |