PeptideDB

Chlorothymol

CAS: 89-68-9 F: C10H13ClO W: 184.66

Chlorothymol (Chlorthymol) is a potent GABAA receptor subunit LGC-37 inhibitor. Chlorothymol is an effective anticonvuls
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Chlorothymol (Chlorthymol) is a potent GABAA receptor subunit LGC-37 inhibitor. Chlorothymol is an effective anticonvulsant. Chlorothymol is protective in several mouse seizure assays, including the 6-Hz 44-mA model of pharmacoresistant seizures[1].
CAS 89-68-9
Formula C10H13ClO
Molar Mass 184.66
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Reference [1]. Alistair Jones, et al. A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant. Epilepsia. 2020 Oct;61(10):2106-2118.