| Bioactivity | Chloroprocaine hydrochloride (2-Chloroprocaine hydrochloride) is a potent inhibitor of Na,K-ATPase activity with an IC50 of 13 mM. Chloroprocaine hydrochloride blocks peripheral nerve[1]. |
| Target | IC50: 13 mM (Na,K-ATPase) |
| In Vivo | In mice, the intravenous LD50 of Chloroprocaine hydrochloride is 97 mg/kg and the subcutaneous LD50 of Chloroprocaine hydrochloride is 950 mg/kg[1]. |
| Name | Chloroprocaine hydrochloride |
| CAS | 3858-89-7 |
| Formula | C13H20Cl2N2O2 |
| Molar Mass | 307.22 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
| Reference | [1]. H Kutchai, et al. Inhibition of the Na,K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43(4):399-403. [2]. Chloroprocaine HCl Injection. |
Chloroprocaine hydrochloride
CAS: 3858-89-7 F: C13H20Cl2N2O2 W: 307.22
Chloroprocaine hydrochloride (2-Chloroprocaine hydrochloride) is a potent inhibitor of Na,K-ATPase activity with an IC50
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