| Bioactivity | Chitinase-IN-5 (8i) is a potent chitinase OfChi-h inhibitor with an IC50 value of 0.051 μM. Chitinase-IN-5 shows good insecticidal activity, it can be used for the research of green pest control and management[1]. |
| Target | IC50: 0.051 μM (OfChi-h) |
| Invitro | Chitinase-IN-5 (0-1 μM; 20 min) inhibits 73.2% activity of OfChi-h at a concentration of 1μM and with an IC50 value of 0.051 μM[1].Chitinase-IN-5 (100-500 μg/mL; 48 h) exhibits high activity with mortality rates over 80% at 500 μg/mL against P. xylostella, which is much higher than that of the control drug hexaflumuron, and inhibits 32.5% Ostrinia nubilalis[1]. |
| Name | Chitinase-IN-5 |
| Formula | C20H21ClFN7 |
| Molar Mass | 413.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dong L, et al. Discovery of Azo-Aminopyrimidines as Novel and Potent Chitinase OfChi-h Inhibitors via Structure-Based Virtual Screening and Rational Lead Optimization. J Agric Food Chem. 2022 Sep 19. |