| Bioactivity | Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 9 can be used in the research of fungi infection[1]. |
| Target | Chitin synthase |
| Invitro | Chitin synthase inhibitor 9 (compound 9j, 300 μg/mL) inhibits chitin synthase (CHS) by 60%[1].Chitin synthase inhibitor 9 (0.0625-0.25 μM, 24 h) shows antifungal activities[1]. Cell Viability Assay[1] Cell Line: |
| Name | Chitin synthase inhibitor 9 |
| Formula | C24H25N3O6 |
| Molar Mass | 451.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yajie Xu, et al. Spiro[benzoxazine-piperidin]-one derivatives as chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2022 Aug 31;243:114723. |