| Bioactivity | Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2]. |
| CAS | 148796-51-4 |
| Formula | C19H34O4 |
| Molar Mass | 326.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980. [2]. Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4. |
Chaetomellic acid A
CAS: 148796-51-4 F: C19H34O4 W: 326.47
Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-
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