| Bioactivity | ChEs/MAOs-IN-1 (Compound 4i) is a dual inhibitor of cholinesterases (ChEs) and monoamine oxidases (MAOs).ChEs/MAOs-IN-1 has IC50 values of 0.048 μM, 0.89 μM, 3.58 μM, and 0.095 μM for AChE, BChE, MAO-B and MAO-B respectively. ChEs/MAOs-IN-1 can be used in the study of neurodegenerative diseases[1]. |
| Target | IC50: 0.048 μM (AChE).IC50: 0.89 μM (BChE).IC50: 3.58 μM (MAO-A).IC50: 0.095 μM (MAO-B).. |
| Name | ChEs/MAOs-IN-1 |
| Formula | C15H10Cl2N2O3 |
| Molar Mass | 337.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kumar, V Pavan et al. Exploration of a library of piperonylic acid-derived hydrazones possessing variable aryl functionalities as potent dual cholinesterase and monoamine oxidase inhibitors. Molecular diversity vol. 27,6 (2023): 2465-2489. |