| Bioactivity | Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3]. | |||||||||
| Name | Cetirizine-d8 | |||||||||
| CAS | 774596-22-4 | |||||||||
| Formula | C21H17D8ClN2O3 | |||||||||
| Molar Mass | 396.94 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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| Reference | [1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993. [2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. |
Cetirizine-d8
CAS: 774596-22-4 F: C21H17D8ClN2O3 W: 396.94
Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated meta
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