| Bioactivity | Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties[1][2]. |
| Invitro | Cerebrocrast (25 μM) 抑制大鼠肝线粒体内线粒体阴离子通道，其 IC50 值为 10.5 ± 2.0 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Cerebrocrast 相关抗体: |
| CAS | 118790-71-9 |
| Formula | C26H35F2NO7 |
| Molar Mass | 511.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fernandes MA, et al. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Mitochondrion. 2005 Oct;5(5):341-51. |
Cerebrocrast
CAS: 118790-71-9 F: C26H35F2NO7 W: 511.56
Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane l
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