Bioactivity | Cerberin is a cardiac glycoside that has been found in C. odollam and has cytotoxic and cardiac modulatory activities. It is cytotoxic to KB and NCI H187 cancer cells (IC50s=1.92 and 1.24 μg/mL).1 Cerberin inhibits Na+/K+-ATPase, increasing intracellular sodium levels and action potential duration in cardiac cells. |
CAS | 25633-33-4 |
Formula | C32H48O9 |
Molar Mass | 576.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Laphookhieo, et al. Cytotoxic cardenolide glycoside from the seeds of Cerbera odollam. Phytochemistry 65(4), 507-510 (2004). |