| Bioactivity | Cemadotin (LU103793) (hydrochloride) is a water-soluble synthetic analogue of Dolastatin 15 (HY-P1126) that inhibits cell proliferation in vitro and the growth of tumor xenografts in mice. Cemadotin (hydrochloride) binds to tubulin and suppresses microtubule dynamics with antitumor activities[1]. |
| CAS | 172837-41-1 |
| Formula | C35H57ClN6O5 |
| Molar Mass | 677.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jordan MA, et al. Suppression of microtubule dynamics by binding of cemadotin to tubulin: possible mechanism for its antitumor action. Biochemistry. 1998 Dec 15;37(50):17571-8. |
Cemadotin hydrochloride
CAS: 172837-41-1 F: C35H57ClN6O5 W: 677.32
Cemadotin (LU103793) (hydrochloride) is a water-soluble synthetic analogue of Dolastatin 15 (HY-P1126) that inhibits cel
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