PeptideDB

Cefodizime

CAS: 69739-16-8 F: C20H20N6O7S4 W: 584.67

Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime ha
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Bioactivity Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts[1][2].
Invitro Enterobacteriaceae including Escherichia coli, Klebsiella pneumoniae, Morganella morgan ii, Proteus mirabilis, Proteus vulgaris, Shigella sonnei, Yersinia enterocolitica and Salmonella species are all consistently sensitive to Cefodizime in vitro. Cefodizime has marginal but variable inhibitory activity against Citrobacter species including Citrobacter freundii, and Serratia marcescens. Cefodizime inhibits other Gram-negative bacteria including Haemophilus irifluenzae, Moraxella catarrhalis, Neisseria gonorrhoeae and Neisseria meningitidis[1]. Cefodizime is a bactericidal antibiotic having high affinity for penicillin-binding proteins lA/B, 2 and 3 of E. coli. The in vitro concentrations of Cefodizime resulting in bactericidal activity against susceptible strains of Gram-positive and Gram-negative bacteria are generally similar to the minimum inhibitory concentrations[1].
Name Cefodizime
CAS 69739-16-8
Formula C20H20N6O7S4
Molar Mass 584.67
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month