PeptideDB

Cbz-Gly-Pro-Ala-O-cinnamyl

CAS: F: C27H31N3O6 W: 493.55

Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) is a small peptide targeting BACE-1 and AChE with the IC50 values of 0.02 μM a
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) is a small peptide targeting BACE-1 and AChE with the IC50 values of 0.02 μM and 1 μM, respectively. Cbz-Gly-Pro-Ala-O-cinnamyl shows neuroprotective effect and can be used for study of Alzheimer’s disease[1].
Invitro Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) (10 μM, 48 h) 对 Aβ1–42 聚集有 54% 的抑制作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Cbz-Gly-Pro-Ala-O-cinnamyl 相关抗体:
In Vivo Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) (腹腔注射; 10 mg/kg;连续9天) 逆转 Scopolamine (HY-N0296) 对小鼠记忆损伤的影响[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
Formula C27H31N3O6
Molar Mass 493.55
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kaur B, et al. Small Peptides Targeting BACE-1, AChE, and A-β Reversing Scopolamine-Induced Memory Impairment: A Multitarget Approach against Alzheimer's Disease. ACS Omega. 2024;9(11):12896-12913. Published 2024 Mar 4.