Bioactivity | Cbl-b-IN-8 (Compound 293) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.5 nM and 7.8 nM, respectively[1]. |
Target | IC50: 5.5 nM (Cbl-b), 7.8 nM (c-Cbl) |
Name | Cbl-b-IN-8 |
CAS | 2815223-33-5 |
Formula | C35H44F3N7O3 |
Molar Mass | 667.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1. |