Bioactivity | Cbl-b-IN-6 (Compound 246) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1]. |
Target | IC50: 4.4 nM (c-Cbl), 5.8 nM (Cbl-b) |
Name | Cbl-b-IN-6 |
CAS | 2815221-33-9 |
Formula | C30H32F5N5O |
Molar Mass | 573.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1. |