| Bioactivity | Cbl-b-IN-18 (compound 51) is an inhibitor of the E3 ligase Casitas B-lineage lymphoma proto-oncogene B (CPL-B). Cbl-b-IN-18 inhibits the phosphorylation of CPL-B (IC50< 100 nM)[1]. |
| Formula | C33H31F4N7O |
| Molar Mass | 617.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Murugan CHINNAPATTU, et al. Bicyclic heterocyclic compounds as cbl-b inhibitors. Worldwide, WO2024062363A1. 2023-09-18 |