Bioactivity | Cbl-b-IN-13 (Example 520) is a Cbl-b inhibitor with an IC50 of <100 nM. Cbl-b-IN-13 has the ability to activate T-cells[1]. |
Target | IC50: <100 nM (Cbl-b) |
Name | Cbl-b-IN-13 |
CAS | 2368841-85-2 |
Formula | C29H30F3N5O2 |
Molar Mass | 537.58 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Paul A. Barsanti, et al. Inhibitors of cbl-b and methods of use thereof. Patent WO2019148005A1. |