Bioactivity | Cbl-b-IN-11 (Compound 466) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.4 nM and 6.1 nM, respectively[1]. |
Target | IC50: 6.1 nM (c-Cbl), 6.4 nM (Cbl-b) |
Name | Cbl-b-IN-11 |
CAS | 2815225-15-9 |
Formula | C31H35F5N6O |
Molar Mass | 602.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1. |