Bioactivity | Caylin-1 is an inhibitor of MDM2 and an analog of Nutlin-3. Caylin-1 can bind to Bcl-XL and is used in multi-target anticancer research[1][2]. |
Name | Caylin-1 |
CAS | 1207480-88-3 |
Formula | C30H28Cl4N4O4 |
Molar Mass | 650.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shin J S, et al. Structural insights into the dual-targeting mechanism of Nutlin-3[J]. Biochemical and Biophysical Research Communications, 2012, 420(1): 48-53. [2]. Li J, et al. A cell-based high-throughput assay for the screening of small-molecule inhibitors of p53–MDM2 interaction[J]. Journal of biomolecular screening, 2011, 16(4): 450-456. |