| Bioactivity | Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1]. | ||||||||||||
| Invitro | Cavosonstat (N91115), a CFTR modulator, promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stability, with a mechanism of action complementary to CFTR correctors and potentiators[1]. | ||||||||||||
| Name | Cavosonstat | ||||||||||||
| CAS | 1371587-51-7 | ||||||||||||
| Formula | C16H10ClNO3 | ||||||||||||
| Molar Mass | 299.71 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16(3):371-379. |
Cavosonstat
CAS: 1371587-51-7 F: C16H10ClNO3 W: 299.71
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabili
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