Bioactivity | Cathepsin C-IN-6 (compound 2) is a E-64c-hydrazideas based inhibitor of cathepsin C with anti-inflammatory activity. Cathepsin C-IN-6 inhibts activation of neutrophil elastase,exhibits potential efficacy in inflammatory diseases with high neutrophil load (e.g.,chronic obstructive pulmonary disease)[1]. |
Target | Cathepsin C |
Name | Cathepsin C-IN-6 |
Formula | C24H35N5O4.xC2HF3O2 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tromsdorf N, et al. E‐64c‐hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1’‐S2’area[J]. ChemMedChem, 2023: e202300218.. |