| Bioactivity | Caspase-3/7 activator 2 is an effective activator of Caspase-3/7. Caspase-3/7 activator 2 has tumor selectivity, anti-proliferative activity and high Apoptosis-inducing ability[1]. |
| Invitro | Caspase-3/7 activator 2 (Compound 7j) 对 Wi-38、Caco-2 和 HepG-2 细胞有抑制作用，IC50 值分别为 16.764 µM、0.069 µM、0.087 µM[1]。Caspase-3/7 activator 2 (0.06 μM；72 h) 显著抑制 Caco-2 细胞凋亡抑制物 Bcl2 的表达 (下调 Bcl2 0.127 倍)。Caspase-3/7 activator 2 对 Caco-2 和 HepG-2 细胞形态无显著影响[1]。Caspase-3/7 activator 2 (0.069 µM；72 h) 有诱导 Caco-2 细胞凋亡的潜力 (凋亡细胞总数为 52.650 %)[1]。 Apoptosis Analysis[1] Cell Line: |
| Name | Caspase-3/7 activator 2 |
| Formula | C32H34N2O7 |
| Molar Mass | 558.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Caspase-3/7 activator 2
CAS: F: C32H34N2O7 W: 558.62
Caspase-3/7 activator 2 is an effective activator of Caspase-3/7. Caspase-3/7 activator 2 has tumor selectivity, anti-pr
Data collection：peptidedb@qq.com
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