| Bioactivity | Caspase-3 activator 4 (compound 4o) is a potent and cross the blood-brain barrier caspase-3 activator. Caspase-3 activator 4 shows antiproliferative activity. Caspase-3 activator 4 induces apoptosis. Caspase-3 activator 4 increases the gene expression of TNF-α. Caspase-3 activator 4 decreases the protein expression of cleaved caspases 3/caspases 3[1]. |
| CAS | 1817874-62-6 |
| Formula | C31H27N5O3 |
| Molar Mass | 517.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qin X, Xu W, Hu J, Dong Y, Ding R, Huang S, Zhao Z, Chang H, Wang X, Dong S. Structure-activity relationship study of Pseudellone C as anti-glioma agents by targeting TNF/TNFR signaling pathway. Eur J Med Chem. 2024 Aug 26;278:116799. |
Caspase-3 activator 4
CAS: 1817874-62-6 F: C31H27N5O3 W: 517.58
Caspase-3 activator 4 (compound 4o) is a potent and cross the blood-brain barrier caspase-3 activator. Caspase-3 activat
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