Bioactivity | Carvacrol-d3 is deuterated labeled trans-2-Nonenal (HY-W089800). trans-2-Nonenal is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Carvacrol-d3 相关抗体: |
In Vivo | Carvacrol (50 or 100 mg/kg; 腹腔注射) 抑制卡拉胶诱导的小鼠机械性超痛觉[3]。Carvacrol (20, 40 和 80 mg/kg,LPS 注射前六天灌胃) 可减轻大鼠炎症 (减少血清促炎分子水平)[4]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
Formula | C10H11D3O |
Molar Mass | 153.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Khan F, et al. Carvacrol Induced Program Cell Death and Cell Cycle Arrest in Androgen-Independent Human Prostate Cancer Cells via Inhibition of Notch Signaling. Anticancer Agents Med Chem. 2019 Jul 31. [3]. Kara M, et al. Supplemental carvacrol can reduce the severity of inflammation by influencing the production of mediators of inflammation. Inflammation. 2015;38(3):1020-7. [4]. Suntres ZE, et al. The bioactivity and toxicological actions of carvacrol. Crit Rev Food Sci Nutr. 2015;55(3):304-18. |