Carumonam

CAS: 87638-04-8 F: C12H14N6O10S2 W: 466.40

Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam Antibiotic, targeting to penicillin-binding protei

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Bioactivity	Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam Antibiotic, targeting to penicillin-binding protein (PBP). Carumonam exerts highly activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while it weakly and even inactively inhibits Streptococcus pneumoniae and Staphylococcus aureus. Carumonam is resistant to beta-lactamase-mediated hydrolysis[1].
Invitro	Carumonam 对肠杆菌科分离株的 MIC90 为 0.013-25 μg/mL，对铜绿假单胞菌的 MIC90 为 12.5 μg/mL[1]。Carumonam (0-400 μg/mL) 对肠杆菌科和铜绿假单胞菌的 PBP-3 有高亲和力，IC50 与对应的 MIC 值相同或更小[1]。
Name	Carumonam
CAS	87638-04-8
Formula	C12H14N6O10S2
Molar Mass	466.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

7-Hydroxy-4H-chromen-4-one