| Bioactivity | Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1]. |
| Invitro | Carpachromene (0-100 μg/mL, 48 h) 对 HepG2、HepG2/IRM、PLC/PRF/5 和 Raji 癌细胞系具有细胞毒性[1]。Carpachromene (20 μg/mL) 显着提高 HepG2/IRM 细胞中 IR、IRS1、PI3K、Akt、GSK3 和 FoxO1 的蛋白表达比率[1]。Carpachromene (20 μg/mL) 可改善 HepG2/IRM 细胞中的细胞糖原合成[1]。 |
| Name | Carpachromene |
| CAS | 57498-96-1 |
| Formula | C20H16O5 |
| Molar Mass | 336.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alaaeldin R, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26(24):7629. |
Carpachromene
CAS: 57498-96-1 F: C20H16O5 W: 336.34
Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells v
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