| Bioactivity | Cardionogen-2 is a biphasic modulator of cardiogenesis, either promoting or inhibiting heart formation depending on the stage of treatment. Cardionogen-2 inhibits Wnt/β-catenin-dependent transcription in murine embryonic stem (ES) cells and zebrafish embryos[1]. |
| Invitro | 在斑马鱼胚胎和小鼠胚胎干细胞 (ES) 中，Cardionogen-2 治疗可促进原肠胚形成期间和之后的心脏生成，而抑制原肠胚形成之前的心脏形成。Cardionogen-2 诱导的作用可通过增加 Wnt/β-catenin 信号传导活性来拮抗。Cardionogen-2 抑制小鼠 ES 细胞和斑马鱼胚胎中 Wnt/β-catenin 依赖性转录[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Cardionogen-2 相关抗体: |
| CAS | 578755-52-9 |
| Formula | C16H13N5O2S |
| Molar Mass | 339.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ni TT, et al. Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chem Biol. 2011 Dec 23;18(12):1658-68. |
Cardionogen-2
CAS: 578755-52-9 F: C16H13N5O2S W: 339.37
Cardionogen-2 is a biphasic modulator of cardiogenesis, either promoting or inhibiting heart formation depending on the
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