| Bioactivity | Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects[1][2]. | ||||||||||||
| Target | Calcium channel | ||||||||||||
| Name | Carboxyamidotriazole | ||||||||||||
| CAS | 99519-84-3 | ||||||||||||
| Formula | C17H12Cl3N5O2 | ||||||||||||
| Molar Mass | 424.67 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229. [2]. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63. |
Carboxyamidotriazole
CAS: 99519-84-3 F: C17H12Cl3N5O2 W: 424.67
Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-me
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