| Bioactivity | Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent. | ||||||||||||
| Invitro | Canrenone inhibits the production of eortieosterone, 18-hydroxydesoxyeortieosterone, 18-hydroxycorticosterone and aldosterone in a dose-dependent manner[1]. Canrenone dose-dependently reduces platelet-derived growth factor–induced cell proliferation and motility. Canrenone inhibits the activity of the Na+/H+ exchanger 1 induced by platelet-derived growth factor[2]. | ||||||||||||
| Name | Canrenone | ||||||||||||
| CAS | 976-71-6 | ||||||||||||
| Formula | C22H28O3 | ||||||||||||
| Molar Mass | 340.46 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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