| Bioactivity | Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity[1][2]. |
| CAS | 71204-89-2 |
| Formula | C23H34O4 |
| Molar Mass | 374.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kelly A Teske, et al. Synthesis and Evaluation of Vitamin D Receptor-Mediated Activities of Cholesterol and Vitamin D Metabolites. Eur J Med Chem. 2016 Jan 6;109:238–246. [2]. R P Esvelt, et al. Calcitroic acid: biological activity and tissue distribution studies. Arch Biochem Biophys. 1981 Feb;206(2):403-13. |
Calcitroic acid
CAS: 71204-89-2 F: C23H34O4 W: 374.51
Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is t
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