Bioactivity | Calcitonin-13C6,15N4 (salmon) (Salmon calcitonin-13C6,15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption[1]. | ||||||
Sequence | Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-{Arg-13C6,15N4}-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bridge: Cys1-Cys7) | ||||||
Shortening | CSNLSTCVLGKLSQELHKLQTYP-{Arg-13C6,15N4}-TNTGSGTP-NH2 (Disulfide bridge: Cys1-Cys7) | ||||||
Formula | C14013C5H240N4315NO48S2.5C2HF3O2 | ||||||
Molar Mass | 4007.93 | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Reference | [1]. Feigh M, et al. Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats. Br J Pharmacol. 2012 Sep;167(1):151-63. |