| Bioactivity | CYP11B2-IN-2 (Compound 10k) is an inhibitor for enzyme aldosterone synthase CYP11B2 with an IC50 of 0.3 nM. CYP11B2-IN-2 is potential for 18F-labeled PET tracer for the diagnosis of primary aldosteronism[1]. |
| CAS | 2241573-22-6 |
| Formula | C16H13FN2O2 |
| Molar Mass | 284.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Maier P, et al., Fluorinated aldosterone synthase (CYP11B2)-inhibitors for differential diagnosis between bilateral and unilateral conditions of primary aldosteronism. Bioorg Med Chem Lett. 2023 Nov 15;96:129501. |
CYP11B2-IN-2
CAS: 2241573-22-6 F: C16H13FN2O2 W: 284.29
CYP11B2-IN-2 (Compound 10k) is an inhibitor for enzyme aldosterone synthase CYP11B2 with an IC50 of 0.3 nM. CYP11B2-IN-2
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