| Bioactivity | CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1]. | ||||||||||||
| Target | NPBWR1, GPR7 | ||||||||||||
| Invitro | CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line: | ||||||||||||
| Name | CYM 50769 | ||||||||||||
| CAS | 1421365-63-0 | ||||||||||||
| Formula | C24H17ClN2O3 | ||||||||||||
| Molar Mass | 416.86 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9. |