Bioactivity | CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1]. | ||||||||||||
Target | NPBWR1, GPR7 | ||||||||||||
Invitro | CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line: | ||||||||||||
Name | CYM 50769 | ||||||||||||
CAS | 1421365-63-0 | ||||||||||||
Formula | C24H17ClN2O3 | ||||||||||||
Molar Mass | 416.86 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9. |