PeptideDB

CYM 50769

CAS: 1421365-63-0 F: C24H17ClN2O3 W: 416.86

CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1].
Target NPBWR1, GPR7
Invitro CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line:
Name CYM 50769
CAS 1421365-63-0
Formula C24H17ClN2O3
Molar Mass 416.86
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9.