| Bioactivity | CYD-2-11 is a selective Bax agonist with a Ki value of 34.1 nM. CYD-2-11 induces cell apoptosis and shows antiproliferative activity to breast cancer MDA-MB-231 and MCF-7 cell lines with IC50 values of 3.22 and 3.81 μM, respectively. CYD-2-11 suppresses tumor growth in MDA-MB-231 tumor models. CYD-2-11 can be used for the research of breast and lung cancer[1][2]. |
| Invitro | CYD-2-11 (0-100 μM; 48 h) shows anti-proliferation effects to breast cancer cells[1].CYD-2-11 (5 μM; 48 h) selectively binds to Bax protein and induces apoptosis in NSCLC and SCLC cell lines[2]. Cell Proliferation Assay[1] Cell Line: |
| Name | CYD-2-11 |
| CAS | 1425944-22-4 |
| Formula | C22H18N2O3 |
| Molar Mass | 358.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
CYD-2-11
CAS: 1425944-22-4 F: C22H18N2O3 W: 358.39
CYD-2-11 is a selective Bax agonist with a Ki value of 34.1 nM. CYD-2-11 induces cell apoptosis and shows antiproliferat
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